KUMJ | VOL. 21 | NO. 4 | ISSUE 84 | OCTOBER - DECEMBER, 2023

Inverted Papilloma: A Practical Approach to Diagnosis, Management, and Current Controversies
Shrestha BL

Abstract:
Inverted papilloma (IP) is an uncommon sinonasal malignancy primarily affecting middle-aged adults. It is characterized by locally aggressive behavior, a high recurrence rate, and a concerning potential for malignant transformation. The etiology of inverted papilloma remains unclear, although human papillomavirus (HPV) infection has been implicated in up to 40% of cases. Surgical intervention is the mainstay of treatment, with the approach (endoscopic versus external) dictated by the extent and characteristics of the tumor. Rigorous follow-up is mandatory to ensure early detection of local recurrence, which can manifest early or with a delayed presentation.
Keyword : Human papillomavirus, Inverted papilloma, Surgical intervention