KUMJ | VOL. 24 | NO. 2 | ISSUE 95 | APRIL - JUNE, 2026
Intra- and inter-rater Reliability of MRI-based Classifications of Degenerative Changes in the Cervical Spine using Objective Criteria
Shrestha D, Danielsen E, Parajuli B, Karki S, Simkhada S, Grotle M, Nygaard OP, Solberg TK
Abstract: Background
Magnetic resonance imaging (MRI) is the modality of choice for the radiological
evaluation of neck pain, both with and without neurological symptoms. Magnetic
resonance imaging offers a detailed, non-invasive investigation of the spinal cord and
nerve roots without exposing patients to radiation.
Objective
To determine the intra- and inter-rater reliability of clinically relevant magnetic
resonance imaging classifications of degenerative cervical spine changes in a
Nepalese working population.
Method
Standardized magnetic resonance imaging examinations of the cervical segments
C2/3 to C7/Th1 were conducted as part of a cross-sectional, case-control study of
presumably healthy Nepalese males, i.e., professional porters and white-collar
workers. Two radiologists independently assessed nine parameters: Pfirrmann
grade, anterior osteophytes, disc-osteophyte complex, neural foraminal stenosis,
Schmorl’s node, Modic changes, spinal canal stenosis, scoliosis, and kyphosis. The
same parameters were reassessed after a one-week interval. Gwet’s agreement
coefficient (AC1) was the main agreement measure. Cohen’s kappa and tetrachoric
correlation were also reported to improve interpretability of the results.
Result
Intra-rater reliability for both raters ranged from substantial to almost perfect
agreement (AC1: 0.63 to 0.98). Rater II showed somewhat higher agreement than
rater I. Inter-rater reliability was substantial to almost perfect for all findings (AC1:
0.62 to 0.90), except for spinal canal stenosis (AC1: 0.51), which had moderate
agreement.
Conclusion
The intra- and inter-rater reliability of the magnetic resonance imaging findings
classifying degenerative changes in the cervical spine were acceptable among
presumably healthy workers.
Keyword : Degenerative cervical changes, Magnetic resonance imaging, Reliability, Nepal