KUMJ | VOL. 22 | NO. 3 | ISSUE 87 | JULY-SEPTEMBER 2024
Hashimoto’s Thyroiditis with Squamous Metaplasia
Dahal S, Makaju R, Basnet D, Dhakal B, Shrestha B, Maharjan PB
Abstract: Hashimoto’s thyroiditis is an autoimmune inflammatory disease. Although rare,
squamous metaplasia can be seen in Hashimoto’s thyroiditis. We present a case of
19 years female who presented with chief complaint of anterior neck swelling for
three months. Thyroid Stimulating Hormone (TSH) was 3.93 mIU/L. Ultrasonography
neck showed TIRADS (Thyroid Imaging Reporting and Data Systems) 5 lesion. Fine
Needle Aspiration Cytology showed Papillary Thyroid Carcinoma. Histopathological
examination revealed numerous lymphoid follicles of variable size with clusters
of squamous metaplastic cells within the germinal centers of lymphoid follicles
and surrounding fibrosis. Some cells showed nuclear clearing. Diagnosis of
Hashimoto’s thyroiditis with squamous metaplasia was further confirmed by
immunohistochemistry. The case presented here is rare and there are very few
cases reported in literature so far.
Keyword : Hashimoto’s thyroiditis, Squamous metaplasia, Thyroid gland
