KUMJ | VOL. 22 | NO. 1 | ISSUE 85 | JANUARY - MARCH

Plexiform Schwannoma Clinically Masquerading as Thrombosed Vein
Basnet D, Makaju R, Gautam N, Shrestha B, Budhathoki A

Abstract:
Plexiform schwannoma is a rare benign nerve sheath tumor usually located in trunk, head, neck, upper extremities and occasionally in lower extremities. It is usually less than 2 cm in size and generally affects young adults. The tumour is composed of schwann cells and exhibit a plexiform growth pattern both in gross or histologic examination and is frequently accompanied by multinodularity causing serpentine distortion. Plexiform neurofibroma commonly mimics plexiform schwannoma and it is important to differentiate between them, as recurrence and malignant potential are more common with plexiform neurofibroma. We present the case of a 14-year-old female with history of a nodular soft tissue mass over his right foot measuring 11 cm in length. A Doppler scan of the foot was suggestive of thrombosed superficial vein in right foot. The histological evaluation of the mass revealed Plexiform schwannoma. S-100 immunostaining is diffuse and strong confirming the diagnosis of Plexiform schwannoma.
Keyword : Hematoxylin and eosin, Histopathology, Plexiform, Schwannoma