KUMJ | VOL. 14 | NO. 4 | ISSUE 56 | OCT.-DEC. 2016
Reflux Symptom Index and Reflux Finding Score in Diagnosis of Laryngopharyngeal Reflux
Pokharel M, Shrestha I, Dhakal A, Purbey B, Amatya RCM
Abstract: Background
Although laryngopharyngeal reflux is a common condition encountered in
otolaryngological practice, its diagnosis is not very easy because of its indistinct
symptoms
Objective
To assess the efficacy of proton pump inhibitors versus proton pump inhibitors with
lifestyle modification in patients with laryngopharyngeal reflux.
Method
Prospective, analytical study conducted in Department of Otorhinolaryngology
and Head and Neck Surgery at Dhulikhel Hospital, Kathmandu University Hospital
between January 2015 to January 2016. Eighty two patients with laryngopharyngeal
reflux having Reflux symptom index > 13 and Reflux finding score > 7 were included.
Patients were divided into 2 groups. Group A comprised of patients treated with
proton pump inhibitors alone and Group B with Proton pump inhibitors with lifestyle
modification. Pre and post therapeutic reflux finding score and reflux symptom index
were compared.
Result
The mean reflux symptom index score difference before and after treatment in group
A was 16.70 and group B was 14.58. Similarly, mean reflux finding score difference
before and after treatment in group A was 8.68 and group B was 9.92. Comparison
of reflux finding score and reflux symptom index scores before and after treatment
revealed improvement in both groups and the difference was statistically significant
(p<0.001). However, comparison of pre and post therapeutic and scores between
group A and B, showed no statistical significance.
Conclusion
The extent of symptomatic improvement correlated positively with both proton
pump inhibitor therapy alone as well as with proton pump inhibitor therapy along
with lifestyle modification. Although addition of lifestyle modification offered
incremental benefit for treating laryngopharyngeal reflux, it was not found to be
statistically significant.
Keyword : Laryngopharyngeal reflux, reflux finding score, reflux symptom index