KUMJ | VOL. 17 | NO. 3 | ISSUE 67 | JULY-SEPT. 2019
Clinical Profile and Survival Rate of Interstitial Lung Disease in a Tertiary Care Center of Eastern Nepal
Ghimire RH, Ghimire A, Bimali A, Bista B
Abstract: Background
The clinical profiles of interstitial lung diseases are reported mainly from developed
world. There have been no data from Nepal.
Objective
The objective of this study is to describe clinical profile and survival in Eastern Nepal.
Method
Prospectively collected clinical, radiological and laboratory data of consecutive
patients with Interstitial lung disease from an eastern regional tertiary care center
were analyzed. The recommended official criteria for diagnosing different types of
interstitial lung diseases were followed accordingly.
Result
The study revealed that, 68.0% of the patient’s age was of above 60 years with male
predominance (66.0%). Idiopathic pulmonary fibrosis (79.5%) was the commonest
interstitial lung disease followed by connective tissue disease associated interstitial
lung disease. Persistent cough (97.7%) and dyspnea (95.5%) were the commonest
presentations. Renal impairment, ischemic Heart Disease and anasarca were
significant co morbidities contributing to mortality. Survival rate of the patients was
found to be maximum at 5 months (95%) and minimum at 24 months (42%) from the
diagnosis of the disease.
Conclusion
Widespread use of High-resolution computed tomography has made early
recognition of interstitial lung disease in elderly patients. Well planned large scale
multicenter prospective studies are needed to broaden our understanding about this
serious pulmonary disorder.
Keyword : Clinical profile, Interstitial lung disease, Survival