KUMJ | VOL. 19 | NO. 1 | ISSUE 73 | JAN.-MARCH, 2021
Dyschromatosis Universalis Hereditaria
Bista M, Agrawal S, Agrawal Y
Abstract: Dyschromatosis universalis hereditaria (DUH) is a rare pigmentary genodermatosis
usually inherited in autosomal dominant fashion characterized by multiple pinpoint
to pea-sized hypo- and hyper-pigmented macules arranged in reticulate pattern that
develops within the first few years of life. An 11 years old boy presented with multiple
gradually progressive asymptomatic hypopigmented macules on hyperpigmented
background on trunk, extremities and face since 2 years of age. Family history was
absent. Punch biopsies revealed increased number of melanocytes in the epidermis
with basal cell vacuolar alteration and pigmentary incontinence and perivascular
infiltration by lymphocytes and melanophages in the dermis. We herein present a
sporadic case of dyschromatosis universalis hereditaria.
Keyword : Dyschromatosis universalis hereditaria, Reticulate pigmentation
