KUMJ | VOL. 1 | NO. 3 | ISSUE 3 | JULY-SEPT, 2003
A case report of Gilbert Syndrome
Manandhar SR, Gurubacharya RL, Baral MR, Manandhar DS
Abstract: Gilbert syndrome is benign, often familial condition characterized by recurrent but asymptomatic mild unconjugated
hyperbilirubinemia in the absence of haemolysis or underlying liver disease. If, it becomes apparent, it is not until
adolescence and then usually in association with stress such as intercurrent illness, fasting or strenuous exercise.
Virtually all patients have decreased level of UDP- Glucuronosyltransferase, but there also is evidence for a defect
in hepatic uptake of bilirubin as well. This case is reported due to its rarity. The prevalence of Gilbert syndrome in
U.S is 3-7% of the population
Keyword : Gilbert Syndrome, familial non-haemolytic jaundice, hereditary non-haemolytic bilirubinaemia, lowgrade chronic hyperbilirubinemia
